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The state’s guardian angel? : The Georgian Orthodox Church and human security

The Georgian Orthodox Church (GOC) organisation has 15 departments, which focus on a wide range of areas from missionary work to finance, economy, real estate, ecology and military. This chapter focuses on historical and political contexts that shaped the GOC as an organisation over time. The GOC’s organisation is headed by Patriarch Ilia, while the administrative–operational part is conducted by

Immune functions of intestinal dendritic cells

The intestinal surface is daily challenged with tremendous amount of foreign material derived our diet and from the commensal bacteria that densely populate the mucosal surface. Occasionally the gut mucosa is exposed to pathogens trying to enter our body. The important task of the intestinal immune system is to remain tolerant toward innocuous luminal constituents and to elicit defense responses t

The ecology of the galactic centre : Nuclear stellar clusters and supermassive black holes

Supermassive black holes are found in most galactic nuclei. A large fraction of these nuclei also contain a nuclear stellar cluster surrounding the black hole. Here we consider the idea that the nuclear stellar cluster formed first and that the supermassive black hole grew later. In particular we consider the merger of three stellar clusters to form a nuclear stellar cluster, where some of these c

The distinct seasonality of early modern casual labor and the short durations of individual working years: Sweden 1500-1800

Historical wage studies have never been able to truly or accurately address the changes in the working year. Real wages have almost always been based on the wages of unskilled and casual laborers, typically paid by the day. Their annual incomes are not clear or obvious – the income is directly dependent on how many days they work. Implicitly the literature has assumed that the number of days worke

Swedish paleopathology and its pioneers

This chapter discusses the history of paleopathology in Sweden. Paleopathology of skeletal remains in Sweden is considered a subfield of historical osteology, a discipline that combines the study of human and animal bones from archaeological sites, with roots in the works of Nils-Gustaf Gejvall (1911–1991). The chapter describes the development of the field from its beginnings in paleopathological

The origin of the Milky Way globular clusters

We present a cosmological zoom-in simulation of a Milky Way-like galaxy used to explore the formation and evolution of star clusters. We investigate in particular the origin of the bimodality observed in the colour and metallicity of globular clusters, and the environmental evolution through cosmic times in the form of tidal tensors. Our results self-consistently confirm previous findings that the

Understanding the shape and diversity of dwarf galaxy rotation curves in ΛCDM

The shape and diversity of dwarf galaxy rotation curves is at apparent odds with dark matter halos in a Λ Cold Dark Matter (ΛCDM) cosmology. We use mock data from isolated dwarf galaxy simulations to show that this owes to three main effects. Firstly, stellar feedback heats dark matter, leading to a `coreNFW' dark matter density profile with a slowly rising rotation curve. Secondly, if close to a

Characterizing gravitational instability in turbulent multicomponent galactic discs

Gravitational instabilities play an important role in galaxy evolution and in shaping the interstellar medium (ISM). The ISM is observed to be highly turbulent, meaning that observables like the gas surface density and velocity dispersion depend on the size of the region over which they are measured. In this work, we investigate, using simulations of Milky Way-like disc galaxies with a resolution

Larson's scaling laws, and the gravitational instability of clumpy discs at high redshift

Gravitational instabilities play a primary role in shaping the clumpy structure and powering the star formation activity of gas-rich high-redshift galaxies. Here, we analyse the stability of such systems, focusing on the size and mass ranges of unstable regions in the disc. Our analysis takes into account the mass-size and linewidth-size scaling relations observed in molecular gas, originally disc

A Toomre-like stability criterion for the clumpy and turbulent interstellar medium

We explore the gravitational instability of clumpy and turbulent gas discs, taking into account the Larson-type scaling laws observed in giant molecular clouds (GMCs) and H i, as well as more general scaling relations. This degree of freedom is of special interest in view of the coming high-z interstellar medium surveys and is thus potentially important for understanding the dynamical effects of t

Mechanistic Toxicology : Molecular interactions and underlying mechanisms of dendritic cell activation in skin sensitization

Allergic skin diseases caused by low molecular weight chemical compounds are a major health concern among the general population, especially in certain occupational groups. To limit exposure to such compounds, it is important that thorough risk assessments are performed before products reach the consumer market. Traditionally, such risk assessments have been based on animal tests, but due to sever

Accelerating Radioactive Ion Beams with REX-ISOLDE

The post accelerator REX-ISOLDE is installed at the ISOLDE facility at CERN, where a broad variety of radioactive ions can be addressed. Since the end of 2001 beams at the final energy of 2.2 MeV/u are available. REX-ISOLDE uses a unique system of beam bunching and charge breeding. First a Penning trap accumulates and bunches the ions, which are delivered as a quasi-continuous beam from the ISOLDE

Effect of indigestible residue from foodstuffs on trypsin and pancreatic α‐amylase activity in vitro

Indigestible residues from black beans (B; Phaseolus vulgaris L cv Tacarigua), green beans (G; Phaseolus vulgaris L), carrots (C; Daucus carota L) and rice bran (R; from Oryza saliva L) were prepared by the pepsin/pancreatin method of Hellendoorn et al and their effect on trypsin and pancreatic α‐amylase was evaluated comparing two experimental procedures. When the remaining caseinolytic enzyme ac