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Biomolecular cryocrystallography: Structural changes during flash-cooling

To minimize radiation damage, crystal structures of biological macromolecules are usually determined after rapid cooling to cryogenic temperatures, some 150-200 K below the normal physiological range, The biological relevance of such structures relies on the assumption that flash-cooling is sufficiently fast to kinetically trap the macromolecule and associated solvent in a room-temperature equilib

Fast Proton Titration Scheme for Multiscale Modeling of Protein Solutions

Proton exchange between titratable amino acid residues and the surrounding solution gives rise to exciting electric processes in proteins. We present a proton titration scheme for studying acid-base equilibria in Metropolis Monte Carlo simulations where salt is treated at the Debye-Huckel level. The method, rooted in the Kirkwood model of impenetrable spheres, is applied on the three milk proteins

A computer-based design system for lightweight grippers in the automotive industry

This paper presents the development as well as the architecture of a computer-aided dedicated fixture design system intended to support the design of lightweight (carbon fiber composite) grippers for a major truck company. Lightweight grippers were required due to the increasing production rates in the automotive industry. The current robotic equipment was facing diverse problems during transporta

Graph Matching Constraints for Synthesis with Complex Components

In this paper we present a new method for high-level synthesis that enhances design flexibility, specialization and performance primarily conceived for programmable hardware. New programmable hardware devices often provide fast dedicated components that perform complex computations. Arbitrary complex computations can be efficiently extracted from the CDFG using our new graph matching constraint to

Human aging, muscle mass, and fiber type composition

To assess the age-related loss of muscle mass and to determine the mechanisms behind this aging atrophy, the muscle structure and fiber type composition have been estimated, using invasive and noninvasive techniques. Limb muscles from older men and women are 25-35% smaller and have significantly more fat and connective tissue than limb muscles from younger individuals. Comparisons of muscle biopsi

The bilaterally symmetric rhopalial nervous system of box jellyfish

Cubomedusae, or box jellyfish, have the most elaborate visual system of all cnidarians. They have 24 eyes of four morphological types, distributed on four sensory structures called rhopalia. Box jellyfish also display complex, probably visually guided behaviors such as obstacle avoidance and fast directional swimming. Here we describe the strikingly complex and partially bilaterally symmetrical ne

A dynamic object-oriented model for efficient simulation of fluid dispersion in turbulent flow with varying fluid properties

Dispersion coefficients for turbulent flow are commonly available, but the common models are not easily implemented for fast computation of dispersion in time-dependent large flow systems. Criteria were developed to aid in the choice of parameters for a model combining plug flow with the N-continuously stirred-tanks model to obtain the best agreement with the pure axial-dispersed plug-flow model,

"Man måste bevisa att man inte är kriminell längre" - En kvalitativ studie om före detta kriminellas erfarenheter av sin återintegrering i samhället

The aim of this study has been to shed light on former criminals' experiences of their own reintegration into society, and to gain a better insight of how social services and probation services has played a part in that process. The study is based on eight semi structured interviews with former criminals’ who are currently active in the organisation KRIS. In order to analyze our empirical mate

Managing Multiple Engine Development Projects - A tool for planning, progress tracking, resource forecasts, and presentations

Result This thesis has resulted in a new Project Management (PM) tool for the Scania Engine Development Project Coordination group, customized for engine development long-term test planning and tracking. The PM tool also shows resource use, capacity, and forecast of all Scania’s engine test benches located in Sweden, Germany and Brazil. Issue of study As a result of the continuously increasing

Swedish Public Administration in Transition: Implications of AI Implementation A qualitative study on how key informants perceive and understand AI implementation in the Swedish public sector and administration structures

With fast technological development, Artificial Intelligence (AI) is one of the most revolutionary forces. Many organizations worldwide are adopting the technology, including the Swedish public sector and administration. Interviewing eight key informants who actively work with implementing AI into the Swedish public sector and administration structures, this thesis aims to investigate how they per

Off-Shell Recursion with Orthogonal Multiplet Bases for Computing Gluon Amplitudes

När två protoner, accelererade till nära ljusets hastighet, krockar i den 27 km långa partikelacceleratorn under den fransk-schweiziska gränsen vid CERN, världens centrum för partikelfysik, så bildas dussintals energetiska sub-atomära partiklar. Den vanligaste partikeln som bildas kallas för gluon, efter engelskans "glue" som betyder lim. Detta namn har den fått eftersom den fungerar somCalculating the color factor of matrix elements for gluon processes is difficult since the gauge group of QCD, SU(3), is non-Abelian. The most commonly used methods for treating color structure all scale as the square of a factorial with the number of gluons, making calculations with more than a few gluons too time-consuming to carry out on demand. This thesis will provide an alternative approach

Concept development of GPX Instrument and GPX Move

In food production facilities, packagings are quality inspected to ensure proper sealing and correct atmo- sphere within. The project was done in collaboration with Gasporox AB (publ), a company developing and producing quality inspection instruments. The goal of the project was to develop a new version of an exiting instrument of theirs. In addition to that, develop a portable inspection de

Sätt barns rättigheter i centrum - En analys om eventuella brister i förhör med barn utsatta för sexuella övergrepp

Det är viktigt att ha en fungerande lagstiftning för att kunna ge barn som blivit utsatta för sexuella övergrepp ett bra rättsligt skydd. FN:s kommitté för barnets rättigheter om Barnkonventionens genomförande, riktade kritik mot Sverige för att inte leva upp till barnets bästa. Kritiken som fördes fram rörde främst att yrkesverksamma har otillräcklig utbildning och att straffprocessen är utdragenIt is important to have an effective legislation in order to provide good legal protection to children who have been sexually abused. The United Nations Rights of the Child committee criticized Sweden for providing insufficient training to relevant professionals on the best interest determination and that the legal proceedings which involve child victims are protracted. To live up to the demands o

Glacifluviala avlagrings- och erosionsformer i sydöstra Skåne : en sedimentologisk och geomorfologisk undersökning

Weichselisens avsmältningsskede i Skåne var mycket komplicerat, vilket har föranlett en stundtals svårtolkad glacialmorfologi. I de norra och centrala delarna av Skåne retirerade isen mot norr och nordost, samtidigt som södra Skåne och Danmark berördes av lobformade isframstötar från en baltisk isström från söder- och sydost. Sedan länge har forskning pågått för att finna lösningen på isens rörelsThe deglaciation of the Weichselian ice sheet was very complicated and the resulting landscape has been perplexing different researchers throughout the 20th century. In the northern parts of Scania, the ice sheet receded towards north and northeast, while a dynamic ice stream with fast flowing ice influenced southern Scania and Denmark. The earlier researchers have mainly focused on striae, the di

En jämförelse av inställningen till delat ledarskap mellan elitidrottare och personer anställda i projektorganisationer

The aim of this study was to evaluate athletics and employees in organizations based on projectstrategies attitude to a shared leadership. Our ambition was to see similarities and differences between the two groups. We used a qualitative approach based on semistructured interviews. The interview guide was designed after Multidimensional Model of Sport Leadership, which describes the complexity of

Parallel and Distributed Graph Cuts by Dual Decomposition

Graph cuts methods are at the core of many state-of-the-art algorithms in computer vision due to their efficiency in computing globally optimal solutions. In this paper, we solve the maximum flow/minimum cut problem in parallel by splitting the graph into multiple parts and hence, further increase the computational efficacy of graph cuts. Optimality of the solution is guaranteed by dual decomposit

Handling and Transportation of Micro Components in Manufacturing

During the last 10 years there has been a constantly increasing demand for micro products and components. The market demand smaller, more functional and better products. The main industries that trigger this demand are the electro-mechanical products. Problem with manufacturing these micro components has occurred with use of conventionally machines. Micro products often demands special working env

Development of the Packaging Material Process at Plastal AB Simrishamn

In the automotive industry, it is common that the customers provide the suppliers with the necessary packing material needed for delivery of the goods. The reason for this is that it makes the handling and unpacking of incoming goods at the customer easy, but it also makes sure that the quality of the packing material is high, and that the transportation damages of the goods are minimised. It shou

When errors become the rule: A survey of Transformation-Based Learning

Transformation-based learning (TBL) is a machine learning method for sequential classification, invented by Eric Brill (1993, 1995). It is widely used within natural language processing (but surprisingly little in other areas). TBL is a simple yet flexible paradigm, which achieves competitive or even state-of-the-art performance in several areas and does not overtrain easily. It is especially suc