Search results

BACKGROUND: Methylmercury (MeHg) is present in fish and is a neurotoxicant at sufficiently high levels. One potential mechanism of MeHg toxicity early in life is epigenetic dysregulation that may affect long-term neurodevelopment. Altered DNA methylation of nervous system-related genes has been associated with adult mental health outcomes.OBJECTIVE: To assess associations between prenatal MeHg exp

Michelson interferometers have been routinely used in various applications ranging from testing optical components to interferometric time-resolved spectroscopy measurements. Traditionally, plate beamsplitters are employed to redistribute radiation between the two arms of an interferometer. However, such an interferometer is susceptible to relative phase fluctuations between the two arms resulting

Plasma levels of tau phosphorylated at threonine-217 (p-tau217) is a candidate tool to monitor Alzheimer's disease. We studied 150 cognitively unimpaired participants and 100 patients with mild cognitive impairment in the Swedish BioFINDER study. P-tau217 was measured repeatedly for up to 6 years (median three samples per person, median time from first to last sample, 4.3 years). Preclinical (amyl

Farmers know much more than we think, and they are keen to improve their knowledge in order to improve their farms and increase their income. On the other hand, decision-makers, organizations, and researchers are increasing their use of citizen volunteers to strengthen their outcomes, enhance project implementation, and approach ecosystem sustainability. This paper assesses the role of citizen sci

Gambling disorder is associated with severe financial, social, and psychological consequences, but treatment-seeking rates have been described to be low. Apart from formal treatment, motivational interventions in nontreatment-seeking high-risk gamblers have been shown to be promising. However, little is known about the effectiveness and acceptability of such motivational interventions carried out

To predict the final geometry in thermo-mechanical processes, the use of modeling tools is of great importance. One important part of the modeling process is to describe the response correctly. A previously published mechanism-based flow stress model has been further developed and adapted for the nickel-based superalloys, alloy 625, and alloy 718. The updates include the implementation of a solid

The present work illustrates the potential of a new diagnostic technique that allows the measurement of the coronal magnetic field strength in solar active regions by utilizing a handful of bright Fe x and Fe xi lines commonly observed by the high-resolution Hinode/EUV Imaging Spectrometer (EIS). The importance of this new diagnostic technique is twofold: (1) the coronal magnetic field is probably

Sterile liver inflammation and fibrosis are associated with many liver disorders of different etiologies. Both type 1 and type 2 inflammatory responses have been reported to contribute to liver pathology. However, the mechanisms controlling the balance between these responses are largely unknown. Natural killer T (NKT) cells can be activated to rapidly secrete cytokines and chemokines associated w

This paper describes a search for beyond the Standard Model decays of the Higgs boson into a pair of new spin-0 particles subsequently decaying into b-quark pairs, H→aa→(bb¯)(bb¯), using proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider at center-of-mass energy s=13 TeV. This search focuses on the range 15 GeV≤ma≤30 GeV, where the decay products are collimat

Background: The Mendelian Society of Lund launched Hereditas in 1920. The purpose of this article is to give an overview of Hereditas’s hundred-year existence, focusing on the conditions for a learned society to publish a scientific journal, and the journal’s importance for the publication and dissemination of genetic research. The article focuses on the historical development of the journal and a

The cosmic origin of fluorine, the ninth element of the periodic table, is still under debate. The reason for this fact is the large difficulties in observing stellar diagnostic lines, which can be used for the determination of the fluorine abundance in stars. Here we discuss some recent work on the chemical evolution of fluorine in the Milky Way and discuss the main contributors to the cosmic bud

Background: Women account for 60% of all stroke deaths and are more often permanently disabled than men, despite their higher observed stroke incidence. Considering the clinical population affected by stroke, an obvious drawback is that many pre-clinical and clinical studies only investigate young males. To improve therapeutic translation from bench to bedside, we believe that it is advantageous t

Adeno Associated Virus (AAV)-mediated gene expression in the brain is widely applied in the preclinical setting to investigate the therapeutic potential of specific molecular targets, characterize various cellular functions, and model central nervous system (CNS) diseases. In therapeutic applications in the clinical setting, gene therapy offers several advantages over traditional pharmacological b

This study is the first to evaluate the setting up aid (SUA), in the Rural Development Programme. For Sweden, we investigate if the aid, firstly, speeds up the transition process to become manager of a farm and, secondly, affects income from farming and survival of the farm. The approach builds on a regression discontinuity design and explores an age 40-the eligibility requirement in the SUA. We f

One of the basic requirements of today's sophisticated world is the availability of electrical energy, and neglect of this matter may have irreparable damages such as an extensive blackout. The problems which were introduced about the traditional power grid, and also, the growing advances in smart technologies make the traditional power grid go towards smart power grid. Although widespread utilisa

Det finns många teorier och mycket tidigare forskning om autonomi och professionellt handlingsutrymme, men kunskapen om i vilken utsträckning rädslan för att utsättas för arbetsrelaterat våld begränsar denna autonomi och handlingsutrymme är begränsad. Denna artikel bygger på en enkätstudie (N =1,236) och jämför svenska socialarbetares, lärares och journalisters erfarenheter av arbetsrelaterat våldAlthough many theories have been developed and a great amount of research has been conducted on autonomy and professional discretion, knowledge on the extent to which fear of being subjected to workplace violence might restrict such autonomy and professional discretion being used is limited. This article draws on a survey study (N=1,236) and compares the experiences of workplace violence of Swedis

African countries such as Nigeria are anticipated to be more susceptible to the impacts of climate change due to reliance on rainfed agriculture. In this regard, the impacts of climate change on crop water requirements (CWR), yields and crop water productivity (CWP) of soybean in the Ogun-Ona River Basin, Nigeria, were evaluated for the baseline period (1986–2015) and future period (2021–2099) und

The decomposition of lignocellulose in nature, as well as when used as feedstock in industrial settings, takes place in a dynamic system of biotic and abiotic reactions. In the present study, the impact of abiotic reactions during the storage of pretreated lignocellulose on the efficiency of subsequent saccharification was investigated. Abiotic decarboxylation was higher in steam-pretreated wheat